insurance dropping glp-1 States cutting back on coverage of Ozempic and other drugs for weight loss More states consider dropping GLP-1

For CY 2026, we proposed to reduce payments for non-drug items and services for hospitals for whom the annual reduction to payment amounts under 419.32(b)(1)(iv)(B)(12) applies with a 2 percentage point reduction to the OPD fee schedule increase factor, explained in more detail in section V.B.7

Rapikovski et al

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Understanding CJC-1295: DAC vs No DAC CJC-1295 without DAC (Mod GRF 1-29) Half-life: 30 minutes to 1 hour Dosing: 1-3 times daily Best for: Mimicking natural pulsatile GH release Recommended for Ipamorelin combo: YES CJC-1295 with DAC Half-life: ~8 days Dosing: Once or twice weekly Pattern: Sustained GH elevation (plateau, not pulses) Recommended for Ipamorelin combo: Not ideal For the Ipamorelin combination, CJC-1295 without DAC is strongly preferred because it creates natural GH pulses rather than constant elevation, which can lead to receptor desensitization

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