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Tirzepatide dramatically improves insulin sensitivity

It is not recommended to use GLP-1 therapies like Trulicity and Victoza (liraglutide) if there is a family history of medullary cell carcinoma of the thyroid or Multiple Endocrine Neoplasia Type 2 (MEN 2)

Diabetes care 34 (3), 697702

Certain thyroid conditions carry additional considerations: people with a history of medullary thyroid cancer or MEN syndrome cannot use GLP-1 medications due to FDA warnings

Laird, Aisling M

Thus, future studies are needed to identify robust biomarkers and establish precise definitions to improve diagnostic accuracy, prevent misdiagnosis, and reduce the impact on patients quality of life