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Filiou, M

Research from the University of Oxford found that those who stop regain weight steadily, returning close to their original size within approximately 1.7 years [BMJ, 2026]

Women appear to be more likely to experience depression due to chronic stress, whereas men may be more likely to develop substance use disorders due to chronic stress

Here are some major takeaways: Weight loss continued for more than a year The analysis showed an average weight loss of just over 10% for people who used semaglutide, the active ingredient in Wegovy, compared with 1.5% for study participants who got a placebo

The pattern is remarkably consistent across patients, though individual experiences vary

Notably, this patient cohort included HP and sarcoidosis patients at different disease stages including such with resolving disease