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The new US Administrations broader policy goals to rebalance prices between the US and rest of world brought new challenges in the UK: in September 2025, Eli Lilly implemented a UK-wide list price increase of up to 170% for Mounjaro paid for out-out-pocket, where the UK will be a 2bn+ market by the end of 2025

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An imbalance exists between the production of ROS and the capacity of antioxidants within the cell gives rise to oxidative stress, a condition linked to irreversible cellular damage that ultimately causes hearing loss due to auditory impairment (Wang and Puel 2018)

Lehmann, M., Haury, K., Oster, H

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