For myocardial infarction, GLP-1RAs alleviate and repair MI via SIRT1/Parkin/mitophagy, insulin-like growth factor-1/2 and upregulating -estrogen receptor
For instance, GLP-1 treatment attenuates the endotoxin-induced release of the potent proinflammatory cytokine IL-1 [71], which is known to inhibit neuronal transmission and promote apoptosis [72]
[1] Incretins such as GLP-1 inhibit glucagon release from the alpha cells of the islets of Langerhans
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There wasnt really clear evidence that GLP-1s were going to directly impact the actual mechanisms of Alzheimers neurodegeneration, he told Being Patient
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