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They were primarily introduced to treat type 2 diabetes, and in recent years their use for weight management has soared particularly in the US, where data suggests around 12% of adults have taken them for this purpose
I also know that inflammation is one of the biggest culprits for disease progression
So, uncertainty remains about safety in this population and caution is advised, noting that this concern really only applies to those with the most severe heart failure
Less frequent but more severe side effects involve pancreatitis, gall bladder issues, kidney complications linked to dehydration, or serious allergic reactions
Initial medicines | Type 2 diabetes in adults: management NG28
Toll-like receptors (TLRs) play a key role in microorganism and viral particle recognition and activation of the innate immune system (Sasai and Yamamoto, 2013
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