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Mutations in these epigenetic regulators can lead to the hyperactivation of WNT signaling that alters dendritic and spinal morphology to underlie ASD-like behaviors, including circuit dysfunction and social deficits

PMID: 1677770

However, some orally-administered drugs are able to avoid first-pass metabolism , to some degree at least, as a result of lymphatic drug absorption

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We identified clomiphene as an undeclared API in five samples, together with tadalafil, sildenafil, dapoxetine, and cardarine (Table 2)

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