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Better endothelial function means lower risk of hypertension and vascular inflammation
Lower dose semaglutide (0.1, 0.2 and 0.4 mg) improved non-alcoholic steatohepatitis (NASH) in another trial (mean age 55.9 years, but the inclusion of older adults up to 75 years)
This tool evaluates several domains: randomization process, deviations from intended interventions, missing outcome data, measurement of the outcome, and selection of the reported result
Key Takeaway Orforglipron is poised to become the first oral, non-peptide GLP-1 receptor agonist approved for obesity treatment
Statements Data availability statement No datasets were generated or analyzed for this study