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Figure 2 3 Cirrhosis-related appetite disorders, restrictive diet, and malnutrition 3.1 Prevalence, risk factors and mechanisms Chronic liver failure in end-stage cirrhosis often leads to low appetite, nutritional deficits, and malnutrition

This review examines studies on iron metabolism, regulation via the hepcidin-ferroportin pathway, myocardial energy, oxidative stress, and clinical trials of iron supplementation or reduction in heart failure, chronic kidney disease, the elderly, women, and athletes

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doi: 10.3390/ijms24076212 12 BalintL.SocaciuC.SocaciuA

The 15-residue synthetic fragment was numbered 157 within the original research nomenclature used by the discovering group, producing the BPC-157 designation that subsequently became the standard name in published literature