The problem is that over time, levels of carnitine decline in all of our tissues, reducing cellular energy production and metabolic activity
& Muzumdar, R
Minimizing Discomfort We help Nocatee patients minimize side effects through gradual dose escalation (start low, increase slowly), eating smaller, more frequent meals, avoiding very fatty or greasy foods, staying well hydrated, and timing doses strategically
When the body is in a constant state of "fight or flight," it produces high levels of cortisol, which can increase oxidative stress and disrupt the balance of the gut microbiome
Additionally, it assists with restoring metabolic balance and likely encourages beneficial effects of tesamorelin, such as more localized reduction of fat and a normal or better energy balance, all while not exposing the person to elevated or excess hormones beyond safer levels regulated physiologically
As the only enzyme shared between the TCA cycle and the ETC, complex II functions as a key metabolic node that directly feeds carbon and reducing equivalents into mitochondrial respiration and CoQ 10 redox cycling 75,76