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Although these data suggest that GSH depletion per se, at least for a short period of time, is not sufficient to cause cell injury, a prolonged depletion of mucosal GSH leads to severe degeneration of intestinal mucosal epithelial cells, as shown in BSO-treated mice (Martensson et al, 1990)

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It has an important function in the maintenance of RBC homeostasis via the interaction with signal regulatory protein alpha (SIRP) [278]

However, the following cases should be noted: Asthma: Avoid inhaling Glutathione to prevent worsening asthma symptoms