Interestingly, a small study investigating moderate/high alcohol consumption of 375ml white wine per day (42g alcohol) for 1 month reported that alcohol consumption did not increase the average baseline homocysteine concentration but a very high level of folic acid supplementation along with alcohol ingestion was effective at lowering homocysteine ( Rajdl et al, 2016)
ALT, alanine transaminase
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Moderate exercise maintains ROS at normal physiological levels, where ROS act as key signaling molecules to activate the Nrf2 pathway and upregulate the expression of endogenous antioxidants such as HO-1, SOD, and GPx (Merry and Ristow, 2016)
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2e, f), as in our first study (Fig