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John Enn discovered an exopeptide in the saliva of the Gila monster which he named exendin-4

Monthly Provider Re-Review Your provider evaluates: Weight progress Side effects Dose response Refill eligibility Dose Titration Dose adjustments follow the standard GLP-1 titration schedule based on: Weight loss progress Tolerability Side effect profile Unlimited Secure Messaging Ask questions anytime Care team responds within 4 business hours Side Effect Escalation Concerning symptoms are escalated directly to your provider for urgent review

PSG estimates that over 5% of the Medicare Part D population is already taking a GLP-1 for diabetes in 2024, and this number could easily double in the coming years

July 10, 2024

Note: Tirzepatide is technically a dual agonist (GLP-1 + GIP), meaning it targets two hormone receptors for potentially stronger effects

Together, these actions help explain why GLP-1 has become such an important focus in the treatment of obesity and type 2 diabetes