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Two estimands were employed to assess treatment efficacy from different perspectives and accounted for intercurrent events and missing data differently, as described in a previous publication 31

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The monocarboxylate transporter 8 (MCT8) and the organic anion transporting polypeptide 1C1 (OATP1C1) are the most important transporters for thyroid hormones in the CNS (Mazzilli et al

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Gastroenterology 124 : 410421 Williams IR (2004) Chemokine receptors and leukocyte trafficking in the mucosal immune system