One MRS study found reduced glutathione in the medial prefrontal cortex (mPFC) in schizophrenia patients compared with healthy controls [21]
Interestingly, in our sibling cohort we also observe that children with the most severe form of konzo (stage 3), have on average the lowest GPx3 levels as well as the largest difference when compared to unaffected siblings
These adaptations could be considered in knees requiring supplemental mechanical stability
These figures come from a sponsor press release rather than a peer-reviewed manuscript, so they should be read as topline results pending full publication and independent scrutiny encouraging, and broadly consistent with the Phase 2 trajectory, but not yet the fully vetted dataset that regulators and clinicians ultimately rely on
This altered state features truncated carbohydrates known as T or Tn tumor antigens, among which Tn-MUC1, carrying Tn carbohydrates, emerges as a promising candidate for immunotherapy
doi: 10.1371/journal.pone.0289616