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This review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement 2020 (Page et al., 2021)

Thats especially concerning for female athletes, many of whom may already be at risk for relative energy deficiency in sport (RED-S) or female athlete triad, a condition that typically includes under-eating, missing periods, and low bone mineral density

Bottom line from the research: creatine won't directly cause fat loss, but it's a powerful tool for improving body composition when combined with proper training and nutrition

Your plan type often matters more than your state, and several BCBS affiliates have announced plans to reduce or eliminate coverage in 2026

Management: Stay well hydrated