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Moore A, Bidonde J, Fisher E, Huser W, Bell RF, Perrot S, Makri S, Straube S

Some people may feel more pain because their nerves are more sensitized

For instance, depletion of mGSH results in Trx2 oxidation (Zhang et al., 2007), while hypercholesterolemic pigs with selective depletion of mGSH in heart mitochondria, exhibit decreased levels of the mitochondria-specific antioxidant enzymes such as SOD2, Trx2, and Prx3 (McCommis et al., 2011)

Gulati SC, Gaynor J, Esseesse I, Gee T, Little C, Andreeff M , Berman E, Kempin S, Clarkson B

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The two conditions have an interlinking web of causation, where obesity can play a significant role in the development and exacerbation of high blood pressure (hypertension)