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Youll hear people talk about higher heart rates or lower HRV when using GLP-1 therapies, and the discussion often circles around different compounds in the class

Any claims regarding effects of carnitine on fat oxidation or weight loss are, of course, unfounded if carnitine supplementation is unable to increase the carnitine concentration in muscle

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Conclusion/interpretation: We found evidence for adverse offspring effects of GLP-1 agonists and SGLT2 inhibitors also in human studies

Ongoing clinical trials are now looking at long-term effects of retatrutide, including sustained metabolic health and as a long-term treatment for metabolic disorders