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This research was supported by NIH grant RO1 CA105437 (C.M.U.) and NSF grant DMS-0616710 (M.C.R.)

These multidirectional channels, which include microbial metabolites, immune cell movement, extracellular vesicles, and neuronal signals, work together to form an integrated gut-immune-brain network [109]

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Low free GSH may therefore reflect conjugation, protein binding, degradation, or export rather than conversion to GSSG alone

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