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The good news: GLP-1 medications like semaglutide use fine-gauge needles (typically 2931 gauge), which are significantly smaller than those used for vaccines or blood draws, and clinical experience shows most patients report little to no discomfort during the injection itself

Of 17 e-mails sent, four e-mails were returned to sender (the e-mail of the author did not exist or had changed) and 4 e-mails received replies, two of them containing pancreatic cancer data

These changes reflect the loss of GLP-1's effects on appetite centres in the brain and gastric emptying

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Instruct patients to inform healthcare providers prior to any planned surgeries or procedures if they are taking RYBELSUS or OZEMPIC tablets [see Warnings and Precautions (5.9)]

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