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Glutamine dependency and redox balance In addition to glucose and fatty acids, CSCs strongly depend on glutamine metabolism to sustain their bioenergetic and biosynthetic demands
Mitochondrial DNA (mtDNA), which encodes 37 genes essential for protein synthesis and energy production, is particularly susceptible to oxidative damage
2024-04-14
OS: Data curation, Resources, Writing review & editing
CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells
The 5-oxoprolinase may regenerate glutamate from 5-oxoproline, but in an ATP-depleting futile cycle that eventually results in a progressive depletion of ATP and further accumulation of 5-oxoproline (Fig
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