building muscle while on glp 1 a GLP-1 Is Hard—But Possible. This Plan Makes It Much Easier How to Combat Muscle Loss

Ageing-related studies on cannabinoids remain highly fragmented, with substantial variability in product characteristics (e.g., cannabinoid content/strength and formulation), dosing regimens, ligand profiles, treatment durations, administration route and rodent genetic backgrounds

Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

Pimentel M et al

There has been shown benefit on lowering blood pressure, improving blood cholesterol, often leading to less medication needed for the treatment of these conditions, she added

Benefits: Anti - aging

J Am Coll Cardiol 2013 Nov 12 [E-pub ahead of print