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Gastrointestinal symptomsparticularly nausea, vomiting, diarrhoea, and constipationare the most frequently reported adverse effects of GLP-1 receptor agonists, occurring in 2050% of patients depending on the specific agent and dose according to clinical trials and SmPC data

Blood tests may help monitor glucose control, hydration, kidney function, liver-related markers, pancreatic enzymes, metabolic risk, and selected nutritional concerns

Most of them were mild to moderate in severity and improved over time

Beyond glycemia: Comparing tirzepatide to GLP-1 analogues

Based on Phase 3 trial data, Retatrutide appears to produce greater average weight loss than semaglutide (the active ingredient in Wegovy and Ozempic)

Most people report feeling more balanced within the first few weeks, with improvements in energy, clarity, and overall wellness