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To investigate the importance of direct cholesterol interactions in modulating beta cell GLP-1R function, we have screened 12 residues selected from the cholesterol binding sites identified in our cgMD simulations, covering a wide range of occupancy, residence time, ability to tolerate the planned mutation, and varied locations within binding sites in active versus inactive states

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Of particular interest is the action of BPC-157 in the context of cardiac arrhythmias

Key Takeaways Glutathione is a powerful antioxidant that supports skin health by reducing oxidative stress