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Nausea Vomiting Diarrhea Constipation Abdominal pain Indigestion Fatigue Though less common, serious side effects may include pancreatitis, gallbladder problems, kidney issues due to dehydration, and severe allergic or stomach reactions

For researchers, the practical implication is uncertainty

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From Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity: In the remote study, we observe a significantly lower self-reported intake of alcohol, drinks per drinking episode, binge drinking odds, Alcohol Use Disorders Identification Test (AUDIT) scores, and stimulating, and sedative effects in the Semaglutide or Tirzepatide group when compared to prior to starting medication timepoint (within-subjects) and the control group (between-subjects)