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TBI pathogenesis involves a myriad of post-injury responses and secondary damage to brain tissues, culminating in cellular damage and loss [4]

5f), whereas downregulation of GOPX was noticed in 100 mM NaCl (0.83-fold) and WCM (0.6-fold) in relation to control conditions

The peptide was originally characterized by the Sikiric group at the University of Zagreb School of Medicine and has been investigated for over two decades in preclinical research models for its effects on tissue regeneration, angiogenesis, fibroblast migration, and cellular signaling across tendon, ligament, muscle, gastrointestinal, and vascular tissues

Chang C-I, Low HP, Qiu L, Strohsnitter WC, Hsieh C-C

It acts against inflammation by reducing the DNA oxidative damage biomarker , thus enhancing immune response

(3) Fig 1