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It stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it only promotes insulin release when blood sugar levels are elevated

P450 reductase catalysis produces superoxide radicals, which can, in the presence of superoxide dismutase and Fe 3+ , form highly reactive hydroxyl radicals capable of damaging virtually all macromolecules

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Computational and methodological statistics and biostatistics

Key secondary endpoints related to physical fitness were changes from randomization to the end of treatment (weeks 052) in: (1) physical functional performance (time to ascend and descend an 11-step stairway twice)

Cerd-Bernad et al., 2022)