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A higher expression of IL-4 and IL-13 is uncovered in the synovial fluid of early RA rather than established RA, which means IL-4 and IL-13 would be the diagnostic biomarkers for early RA patients (84, 85)

However, there were no statistically significant differences in TNF- ( P = 0.1696), IL-6 ( P = 0.9869) and IL-1 ( P = 0.9179) expression levels between the OA and OA + saline groups (Fig

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(NYSE: MRK) has entered into an exclusive global license agreement with Hansoh Pharmaceutical Group Company Limited (HKEX: 3692) for the development and commercialization of HS-10270 , an investigational oral GLP-1 receptor agonist aimed at treating type 2 diabetes and obesity

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