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Data availability All source data for this work (or generated in this study) are available upon reasonable request

Peptides that are FDA-approved for weight loss such as Wegovy, Zepbound, and Saxenda have gone through extensive testing for safety and efficacy

As of now, research on small molecule GLP-1RAs is still mainly in the laboratory and early clinical trial stages

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In 2021s STEP 1 trial the first and only trial demonstrating the efficacy of semaglutide as a treatment for adult obesity a subset of 140 patients underwent DEXA scans for body composition analysis

They should understand how to combine GLP-1 in Charleston with resistance training, targeted supplementation, hormone optimization, and peptide adjuncts