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36 , 130143 e135 (2024)

J Neurol Neurosurg Psychiatry (2020) 91(8):795808

Goldstein said there are two likely reasons

We need to improve access to these medications

Using evidence-based practices, physicians can use medications to augment weight-loss in patients who have already started to reduce calories and exercise but are still considered overweight by medical standards

10 Targeting these TAS2Rs with bitter compounds targeting extra-oral bitter taste receptors could be a strategy to influence gastrointestinal motility, and potentially impact hunger signals, similar to the use of pharmaceutical GLP-1 agonists