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It's a watershed move that could unlock a vast new patient population for Novo Nordisk and Eli Lilly and dramatically expand access to medications that were previously out of reach for many people ages 65 and above

GLP-1 influences the central nervous system, including areas that regulate appetite and energy balance

You still get substantial GLP-1 and GIP receptor activation with meaningful glucagon engagement

Additionally, people with fair skin may notice bruises more because their blood vessels are closer to the surface, making discoloration more visible

The 30.3% figure is a two-year result in a selected group: people with a BMI of 35 or higher who completed the main trial and tolerated their dose

Glucagon receptor activation increases your body's resting metabolic rate (you burn more calories at rest) and promotes lipolysis (the breakdown of stored fat into fatty acids that can be used for energy)