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If severe B12 deficiency with neurological involvement is suspected, treatment should be initiated promptly without waiting for test results, and specialist advice may be needed

TABLE 2 Characteristics of the included studies

Ferritin is unreliable in cases of inflammation therefore transferrin saturation is more reliable but has a 2 hour window for testing after blood draw for accurate results

If the solution becomes cloudy or discolored, discard and reconstitute a fresh vial