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The incubation of endothelial brain cells with gp120 and Tat reduced the GSH intracellular levels and decreased GSH/GSSG ratio

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Molecular and Cellular Neuroscience 92 (2018 10 Witschi A, Reddy S, Stofer B, Lauterburg B: The systemic availability of oral glutathione

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Mitochondria are particularly vulnerable to oxidative damage, and they maintain their own glutathione pool