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As weve mentioned earlier with skin aging, levels of both glutathione and vitamin C seem to drop as a result of the aging process, leading to similar conditions in elderly individuals
Metformin inhibits melanogenesis by reducing intracellular cyclic adenosine monophosphate (cAMP) accumulation, but its low lipophilicity obligates its use in high concentrations for topical efficacy [62]
J Psychosom Obstet Gynecol
2020;18:eAO4039