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The Von Frey test results demonstrated a substantial reduction in paw withdrawal thresholds in Nrf2 KO mice following MIA injection (Fig
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These findings suggest that NNMT inhibition may influence tumor cell line phenotypes in vitro through both metabolic and epigenetic mechanisms, making 5-amino-1MQ a valuable tool for investigating the metabolic characteristics of different tumor cell lines
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doi: 10.1038/nature14344 84 TarangeloAMagtanongLBieging-RolettKTLiYYeJAttardiLDet al
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