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During this period, insulin promotes lipid synthesis by mediating the expression of sterol regulatory element-binding protein (SREBP)-1 in PDAC cells (Swierczynski et al., 2014

[1] [2] These mechanisms contribute to improved glycemic control and significant appetite reduction, often resulting in substantial caloric restriction

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For example, its likely they wont lead to the same dramatic decrease in appetite

Initially used as a diabetes medication, semaglutide has made headlines as an anti-obesity wonder drug, touted by everyone from Elon Musk to Boris Johnson

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