Rada P, Rojo AI, Evrard-Todeschi N, Innamorato NG, Cotte A, Jaworski T, et al
Adjustments are made one at a time in small (approximately 10%) increments, starting with either the earliest time of high blood glucose in the day or the most crucial time, such as hypoglycemic events
speculation includes endogenous IGF-1 axis suppression or downstream insulin/glucose dynamics
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Nonalcoholic fatty liver disease (NAFLD), now increasingly referred to as metabolic dysfunction-associated steatotic liver disease (MASLD), affects approximately 2530% of adults in the United States
The findings from the FLOW trial have the potential to change the disease course of these high-risk patients and pave the way for new treatment strategies, offering hope to millions of patients globally. Pratley et al note that new research will follow in 2024 and 2025, which will be looking into clinically relevant areas to address the unmet needs of this patient population.