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In severe cases, subacute combined degeneration of the spinal cord may occur [13] [14] Glossitis and mouth ulcers : A sore, red tongue and recurrent oral ulceration Mood changes : Depression, irritability, and in rare cases, psychosis It is important to note that symptoms can be subtle initially, and some individuals remain asymptomatic despite biochemical deficiency

Greenway FL, Fujioka K, Plodkowski RA, Mudaliar S, Guttadauria M, Erickson J, Kim DD, Dunayevich E

Neuroinflammation 8:118

The results showed that NTAPP substantially upregulated the expression levels of CCND1 , LEF1 , and TCF4 as compared with control groups (Fig