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Specific Adverse Effects Reported in Clinical Trials While the overall safety profile was excellent, clinical trials documented all adverse events regardless of severity or causality

Clinical trials in the STEP programme demonstrate average weight loss of 1015% of body weight over 68 weeks with semaglutide, primarily through decreased food consumption rather than metabolic acceleration

You may also decide to not pursue weight loss at this time: having a larger body and even being advised to lose weight does not mean that you must opt to lose weight

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