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14 Most people can manage side effects with dose adjustments or medicines to help with nausea

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Because retatrutide is not an approved public-use medication and has no FDA-approved consumer vial, concentration, or reconstitution instructions, readers should not apply gray-market vial math or assume online products match the investigational drug used in trials [2], [3]

Dehydration can worsen fatigue, dizziness, constipation, and weakness