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Instead of relying primarily on historical relationships, many sponsors are exploring more data-driven approaches to site selection, including: regional disease heatmaps investigator performance analytics patient population modeling AI-assisted feasibility analysis These approaches aim to answer a fundamental question: Which sites can actually recruit the patients required for modern metabolic trials

Further, there were shortages of these medications that created access problems including no new starts and for those who had been on medications, not being able to get their medications in a timely manner