glp-1 overview Agonists Glucagon-like peptide 1 (GLP-1) -

These projections from the area postrema to the RVLM may constitute potential pathways activated by GLP-1 to elicit sympathetic responses

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D&D Pharmatech

PMID: 27295427

This approach can also result in increased production of other hormones produced by L-cells such as oxyntomodulin and peptide YY (PYY), which can enhance the metabolic effects of GLP-1

In 48 weeks: Patients lost up to 24% of their weight on the highest dose