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Musazadeh et al

Semaglutide was added in 2024, and tirzepatide markers were added from 1 January 2026

Appetite drops noticeably within 12 weeks

Wang L, Zehir A, Sadowska J

Nature Communications 2022 13:1 13, 118 (2022)

Thus, liraglutide can be considered an intermediate-acting GLP-1RA providing continuous exposure of the GLP-1 receptor throughout the day, but with clear daily peak and trough plasma concentrations apparently preventing tachyphylaxis on small intestinal motility (32) (Figure 3)