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Furthermore, single-cell sequencing has been successfully used extensively to understand the biology of these tissues (209, 213217)

In a pilot trial in patients awaiting gastrointestinal endoscopy or colorectal cancer resection, the administration of a mixture of three major curcuminoids (2.35 g/day for 14 days) resulted in detectable amounts of curcumin in colonic mucosa (mean concentration, 48.4 g/g of tissue), demethoxycurcumin (7.1 g/g), and bisdemethoxycurcumin (0.7 g/g) (78)

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Mesenchymal stem cells in the treatment of Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD) and the AKI-to-CKD transition