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Full therapeutic effects typically develop over 4-12 weeks depending on the severity and type of injury

It has been postulated that catalase in the liver may confer cellular protection by degrading the hydrogen peroxide to water and oxygen [2831]

The KD causes a state of physiological ketosis, altering brain energy metabolism from glucose to ketone bodies like -hydroxybutyrate and acetoacetate (Crosby et al., 2021)

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In vitro studies using both primary neuronal cultures and transfected neuronal cell lines have been instrumental in understanding the mechanisms of tau hyperphosphorylation and its role in promoting neurotoxicity 170 , 171

Its sociopsychological significance may exceed its biological function, even to the extent of causing cosmetic problems, resulting in lower quality of life and one's self-esteem