This is a more demanding regulatory pathway than small-molecule ANDA bioequivalence, which is why the biosimilar pipeline for any given biologic is thinner than the ANDA pipeline for a comparable small molecule [42]
MCFA Oxidation and Ketogenesis in the Brain It is widely accepted that adult mammals' brain uses almost no LCFA (C14-C18) in energy metabolism (121, 122)
Ardura-Fabregat A, Boddeke EW, Boza-Serrano A, Brioschi S, Castro-Gomez S, et al
This means established recommendations regarding nutrition and physical activity will have to guide most Americans to a healthy body mass index
Physiol Rev 1983;63(4):1420-80
Find out if they work and are safe, including side effects and drug interactions