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Besides, it is important to determine potential resistance mechanisms after inhibiting FSP1 for a long time and to identify deeper mechanisms associated with necroptosis medicated by FSP1 in more clinical cancer models

2 The NHS is now prioritising newer medications like Mounjaro, which received broader NICE approval in 2024

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Thus, determining a clearer understanding of the mechanism of action would allow the initiation of large-scale clinical trials needed to determine the potency, safety, and efficacy of these molecules on neurodegenerative disorders