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Therefore, the balance between ROS production and antioxidant substances in the epididymis is essential for sperm development and maturation

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9, 606612 10.1021/acsmacrolett.0c00118 [DOI] [PMC free article] [PubMed] [Google Scholar] 189.Chaudhuri A., Venkatesh Y., Das J., Gangopadhyay M., Maiti T.K

reported that CB-839 could promote the production of reactive oxygen species (ROS) in colorectal cancer cells, cause nuclear translocation of Nrf2, and subsequently upregulate the expression of uridine phosphorylase 1 (UPP1), which promotes the activation of 5-fluorouracil (5-FU)

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