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It also reduces the chance that cost, social-media claims, or trial headlines drive the decision more than clinical fit

According to the International Diabetes Federation, India is home to approximately 77 million adults with diabetes, expected to rise by 134 million by 2045

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NICD then translocates to the nucleus, where it converts the C-promoter binding factor-1 (CBF-1) complex from a transcriptional repressor to an activator, promoting the expression of Notch target genes

The average number of -end (+) cells from eight coronal sections (between bregma 1.22 and 2.42 mm, 30 m thickness) per mouse was 69935 ( n =4) in iDTR mice (Fig