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The oxidative stress of Hcy in the MTHFR genotype, the residual spike protein S in LC, and reactivated viruses due to persistent lymphopenia conspire to overwhelm mitochondria lacking an antioxidant shield

All patients with active and inactive CD and localization of inflammatory lesions in the large intestine and the ileocecal region were treated with mesalamine (2 g/day)

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Promising treatments targeting the IFN- chemokine axis, JAK-STAT pathway, and Nrf2-ARE pathway, have recently emerged ( Figure 2 )